Product Information |
Product name |
Lacidipine 103890-78-4 |
CAS No. |
103890-78-4 |
Molecular Formula |
C26H33NO6 |
Molecular Weight |
455.543 |
Quality Standard |
99% up, Medicine Grade |
Appearance |
White powder |
COA of Lacidipine |
TEST |
STANDARD |
RESULT |
Appearance: |
A white to pale yellow crystalline powder. Practically insoluble in water; freely soluble in acetone, sparingly soluble in absolute ethanol. |
Confirms |
Identification |
(1) IR: Concordant with the reference spectrum(RS407) |
Conforms |
(2) HPLC: Corresponding to the principle peak |
Conforms |
|
Water |
NMT 0.2% |
0.06% |
Related substances (By HPLC) |
Impurity A: NMT 0.15% Impurity B: NMT 0.15% Impurity C: NMT 0.15% Any individual impurity: NMT 0.10% Total impurities: NMT 0.50% |
ND ND ND ND ND |
Ethanol |
NMT 2500ppm |
172.6ppm |
Methylene Dichloride |
NMT 300ppm |
< 60ppm |
Lead |
NMT 0.5μg/g |
0.0977μg/g |
Assay(By HPLC) |
98%-102% (C26H33NO6on anhydrous basis) |
99.7% |
Conclusion |
Meet the specification of BP2018 |
Usage |
Function of Lacidipine
Lacidipine can be used to treat high blood pressure. This product is a specific, potent and long-lasting dihydropyridine calcium channel blocker, which mainly selectively blocks the calcium channel of vascular smooth muscle, dilates the surrounding arteries, reduces peripheral vascular resistance, reduces cardiac afterload, and lowers blood pressure.