Product Information |
Product name |
Colistin Methanesulfonate Sodium / Colistimethate Sodium |
CAS No. |
8068-28-8 |
Molecular Formula |
C58H105N16Na5O28S5 |
Molecular Weight |
1759.90 |
Quality Standard |
98% up, Medicine Grade |
Appearance |
White powder |
Specification of Colistimethate Sodium |
Category |
Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug |
Standard |
Medical standard |
Shelf life |
2 years |
Storage |
should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Test Item |
Standard: USP |
Identification |
IR spectrum similar to that of RS |
HPLC retention time similar to that of RS |
|
Related substance |
Total impurities: NMT0.3% |
Single impurity: NMT0.1% |
|
Heavy metals |
NMT 10ppm |
Loss on drying |
NMT0.5% |
Residue on ignition |
NMT0.1% |
Assay |
98.5%-101.0% |
Usage |
What is Colistimethate
Sodium
Colistin is a group of polypeptide antibiotics produced by bacillus polymyxa. Among
them, polymyxin B and E have significant antibacterial activity against
gram-negative bacteria, and they are the first choice for the treatment of
Pseudomonas aeruginosa infections.