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CAPECITABINE 154361-50-9

USP 34 , Medical Grade

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Product Detail

Product Information

Product name	Capecitabine
Molecular Formula	C15H22FN3O6
Molecular Weight	359.35
CAS No.	154361-50-9
Quality Standard	USP34, medical grade
Appearance	White powder

COA of CAPECITABINE

Items	Specifications	Results
Apperance	White or off-white crystalline powder	White crystalline powder
Identification	The spectrum of the sample corresponds to that of RS	Meets the requirements
	The retention time of the major peak of the test solution corresponds to that of the RS	Meets the requirements
Specific Rotation	+96.0°~+100.0°	+98.1°
Water	≤0.3%	0.01%
Heavy Metals	≤20ppm	<20ppm
(as Pb)	≤20ppm	<20ppm
Residue on ignition	≤0.1%	0.02%
Assay	98.0%~102.0%	99.70%
	98.0%~102.0%	99.70%

Usage

Function of Capecitabine

Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5'fluorocytidine in the liver by carboxylesterase, and then decellularized by the liver and tumor The action of ammonia enzyme is converted into 5'-deoxy-5 'fluorouridine, and finally catalyzed by thymidine phosphorylase into fluorouracil (5-FU) in tumor tissue.

Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration of this product is significantly higher than blood and muscle levels. The curative effect on various animal tumors is significantly higher than that of 5-FU. This product has a synergistic effect with a variety of anti-tumor drugs.